How to Accept Peptide Payments on BigCommerce

BigCommerce is a popular hosted ecommerce platform that many peptide merchants use for its built-in features and scalability. However, the default payment options available through BigCommerce — including PayPal powered by Braintree and Stripe — do not support peptide or research chemical sales.

BigCommerce does support third-party payment gateway integrations, which means you can connect a high-risk merchant account and process peptide payments through your BigCommerce store without switching platforms.

Unison Payment Solutions provides peptide merchants with a dedicated merchant account and payment gateway compatible with BigCommerce. The integration connects through BigCommerce's payment provider settings, routing transactions through your Unison merchant account instead of restricted default providers.

BigCommerce offers strong built-in features for peptide merchants: customizable checkout, built-in SSL, multi-channel selling, and robust order management. Combined with a properly underwritten high-risk merchant account from Unison, your BigCommerce store can accept credit cards, debit cards, and ACH payments with full account stability.

One advantage of BigCommerce for peptide sellers is its headless commerce capability. If you need a custom frontend with specific compliance messaging and disclaimers, BigCommerce's API-driven architecture supports that while still leveraging the platform's backend for order management and inventory.

Unison provides chargeback prevention, fraud filtering, and billing descriptor configuration as part of the integration. These tools protect your BigCommerce store from the dispute issues that commonly affect peptide merchants.

3 Simple Steps

1. Apply online — Takes less than 10 minutes
2. Get approved — 3–7 business days for high-risk accounts
3. Start processing — Equipment ships pre-configured and ready to go

No Strings Attached

• No long-term contracts
• No early termination fees
• No hidden charges
• Transparent interchange-plus pricing

Switching providers? We analyze your current statement, show your savings, and handle the transition.

The peptides & research chemicals industry is evolving rapidly, and payment processing technology is evolving with it. Understanding the key trends shaping how how to accept peptide payments on bigcommerce businesses accept and manage payments helps you stay ahead of the competition and position your business for long-term growth. Unison Payment Solutions continuously invests in new technology and processing capabilities to ensure our merchants always have access to the most current and effective payment solutions.

Contactless payments have become the norm, with over 50% of in-person transactions now using tap-to-pay or mobile wallet technology. Consumers increasingly expect businesses to offer contactless payment options, and those that do see faster checkout times, shorter lines, and higher customer satisfaction scores. All POS terminals provided by Unison support NFC contactless payments, ensuring your how to accept peptide payments on bigcommerce business meets modern customer expectations.

Integrated business management is replacing standalone payment terminals. Modern POS systems do far more than process transactions — they manage inventory, track employee performance, generate financial reports, facilitate customer loyalty programs, and integrate with accounting software. For how to accept peptide payments on bigcommerce businesses, this integration eliminates manual data entry, reduces errors, and provides real-time visibility into business performance that drives better decision-making.

Consumer financing and buy now, pay later (BNPL) options are driving higher average transaction values across many industries. Offering payment plans through providers like Affirm, Afterpay, and Klarna can increase your average ticket size by 30 to 50 percent while reducing cart abandonment for higher-priced products and services. Unison's consumer financing integration makes it easy to offer flexible payment options to your customers.

Payment processing does not have to drain your profits. But many how to accept peptide payments on bigcommerce business owners lose thousands of dollars a year through avoidable mistakes. Here are the most common issues we see and how to fix them.

Overpaying on Flat-Rate Processing

Flat-rate processors charge the same percentage on every transaction regardless of card type. A debit card that would cost 0.5 percent on interchange-plus gets charged 2.6 percent on flat rate. Once your monthly volume exceeds $5,000, interchange-plus pricing saves real money. The higher your volume the bigger the savings.

Not Reading Monthly Statements

Your processing statement lists every fee you paid last month. Most merchants never look at it. Calculate your effective rate by dividing total fees by total volume. If the result is above 2.5 percent for card-present transactions you are paying too much. Our team will help you read your statement and identify savings.

Ignoring Chargeback Prevention

Each chargeback costs you the transaction amount plus a $25 to $100 fee. Too many chargebacks can put your account into a monitoring program or lead to termination. Simple steps like clear billing descriptors, detailed receipts, and prompt customer service prevent most disputes before they happen.

Using Outdated Equipment

Old terminals that do not support EMV chip or contactless payments expose you to fraud liability and higher interchange rates. Modern terminals process faster, accept all payment types, and qualify for the lowest available rates. Upgrading your equipment often pays for itself within the first month through lower fees and fewer chargebacks.