How to Accept Peptide Payments on Shopify

If you sell peptides through Shopify, you have probably already discovered that Shopify Payments does not support peptide or research chemical sales. Shopify Payments is powered by Stripe, which classifies peptides as a restricted category and will freeze or terminate accounts that process peptide transactions.

This does not mean you cannot sell peptides on Shopify. It means you need a third-party payment gateway connected to a high-risk merchant account that is properly underwritten for peptide sales.

Unison Payment Solutions provides peptide merchants with a high-risk merchant account and payment gateway that integrates directly with Shopify. Your customers check out through your Shopify store as normal, but transactions are processed through Unison instead of Shopify Payments.

The setup process is straightforward. Unison provides you with a payment gateway (such as PayTrace) that connects to Shopify through its third-party payment provider settings. Once connected, your checkout accepts credit cards, debit cards, and ACH payments — all processed through your dedicated peptide merchant account.

Because your account is underwritten specifically for peptide sales, you avoid the sudden shutdowns, frozen funds, and account terminations that happen when peptide merchants try to use Shopify Payments or other platforms not designed for high-risk categories.

Unison also provides chargeback prevention tools, fraud filtering, and billing descriptor configuration to keep your Shopify store running smoothly. If disputes arise, our team helps you manage them before they threaten your account stability.

3 Simple Steps

1. Apply online — Takes less than 10 minutes
2. Get approved — 3–7 business days for high-risk accounts
3. Start processing — Equipment ships pre-configured and ready to go

No Strings Attached

• No long-term contracts
• No early termination fees
• No hidden charges
• Transparent interchange-plus pricing

Switching providers? We analyze your current statement, show your savings, and handle the transition.

The peptides & research chemicals industry is evolving rapidly, and payment processing technology is evolving with it. Understanding the key trends shaping how how to accept peptide payments on shopify businesses accept and manage payments helps you stay ahead of the competition and position your business for long-term growth. Unison Payment Solutions continuously invests in new technology and processing capabilities to ensure our merchants always have access to the most current and effective payment solutions.

Contactless payments have become the norm, with over 50% of in-person transactions now using tap-to-pay or mobile wallet technology. Consumers increasingly expect businesses to offer contactless payment options, and those that do see faster checkout times, shorter lines, and higher customer satisfaction scores. All POS terminals provided by Unison support NFC contactless payments, ensuring your how to accept peptide payments on shopify business meets modern customer expectations.

Integrated business management is replacing standalone payment terminals. Modern POS systems do far more than process transactions — they manage inventory, track employee performance, generate financial reports, facilitate customer loyalty programs, and integrate with accounting software. For how to accept peptide payments on shopify businesses, this integration eliminates manual data entry, reduces errors, and provides real-time visibility into business performance that drives better decision-making.

Consumer financing and buy now, pay later (BNPL) options are driving higher average transaction values across many industries. Offering payment plans through providers like Affirm, Afterpay, and Klarna can increase your average ticket size by 30 to 50 percent while reducing cart abandonment for higher-priced products and services. Unison's consumer financing integration makes it easy to offer flexible payment options to your customers.

Payment processing does not have to drain your profits. But many how to accept peptide payments on shopify business owners lose thousands of dollars a year through avoidable mistakes. Here are the most common issues we see and how to fix them.

Overpaying on Flat-Rate Processing

Flat-rate processors charge the same percentage on every transaction regardless of card type. A debit card that would cost 0.5 percent on interchange-plus gets charged 2.6 percent on flat rate. Once your monthly volume exceeds $5,000, interchange-plus pricing saves real money. The higher your volume the bigger the savings.

Not Reading Monthly Statements

Your processing statement lists every fee you paid last month. Most merchants never look at it. Calculate your effective rate by dividing total fees by total volume. If the result is above 2.5 percent for card-present transactions you are paying too much. Our team will help you read your statement and identify savings.

Ignoring Chargeback Prevention

Each chargeback costs you the transaction amount plus a $25 to $100 fee. Too many chargebacks can put your account into a monitoring program or lead to termination. Simple steps like clear billing descriptors, detailed receipts, and prompt customer service prevent most disputes before they happen.

Using Outdated Equipment

Old terminals that do not support EMV chip or contactless payments expose you to fraud liability and higher interchange rates. Modern terminals process faster, accept all payment types, and qualify for the lowest available rates. Upgrading your equipment often pays for itself within the first month through lower fees and fewer chargebacks.